One thing I admired about this scientist was his curiosity – and willingness to experiment on HIMSELF! He was going to have his wife draw his blood every few hours so he could test one of his questions... I love it!
I get frustrated and discouraged with all of the time and effort that goes into actually getting a clinical study done: the grant writing, waiting, IRB approval, waiting, subject recruitment, waiting, and on and on. I am attracted to the simplicity of experimenting on oneself for certain questions (but of course, not every question could be answered this way).