Thursday, December 31, 2009

Moon day, New Year’s Eve, and habits for 2010

It’s a beautiful and snowy moon day and New Year’s Eve.

I’m working on my 2010 new year’s resolutions and trying something new this year: writing down the habits I want to develop, habits I can practice every day so that I don’t have to think about them anymore.

So, the 6 habits I want to develop in 2010:
1) Buy local and in-season food.
2) Cook 2 new recipes a week and write them down.
3) Avoid sugar.
4) Minimize purchasing things – I want to de-clutter my life.
5) Write (blog, journal) every day.
6) Practice pranayama and take long savasana at the end of practice.

“We are what we repeatedly do. Excellence, then, is not an act, but a habit.” ~Aristotle


Wednesday, December 30, 2009

Asana

It is an amazing feeling to be able to practice with no pain. I have a new appreciation for my body and I will be much more careful with it from now on!

I love what Iyengar writes about asanas, the 3rd limb of Ashtanga:
“Asanas have been evolved over the centuries so as to exercise every muscle, nerve and gland in the body... their real importance lies in the way they train and discipline the mind…
By performing asanas, the sadhaka first gains health, which is not mere existence. It is not a commodity which can be purchased with money. It is an asset to be gained by sheer hard work. It is a state of complete equilibrium of body, mind and spirit. Forgetfulness of physical and mental consciousness is health. The yogi frees himself from physical disabilities and mental distractions by practicing asanas…
The yogi never neglects or mortifies the body or the mind, but cherishes both. To him the body is not an impediment to his spiritual liberation nor is it the cause of its fall, but is an instrument of attainment. He seeks a body strong as a thunderbolt, health and free from suffering so as to dedicate it in the service of the Lord for which it is intended…
Just as an unbaked earthen pot dissolves in water the body soon decays. So bake it hard in the fire of yogic discipline in order to strengthen and purify it.”

Tuesday, December 29, 2009

A good reason to cut out sugar

study recently came out looking at the effect of sugar (glucose) on human cells. They found that glucose changes the activity of telomerase (the enzyme we’re looking at in our study). Telomerase keeps chromosomes long and helps cells live indefinitely, which we want in healthy cells, but do NOT want in cancer cells.

The study looked at both healthy lung cells and precancerous lung cells. They split the cells into two groups: One group received a normal amount of glucose, the other group received lower than normal amounts of sugar.

Results: The healthy cells exposed to lower levels of glucose lived longer, while the precancerous cells exposed to lower levels of glucose died off.

Two genes were affected by the restriction of glucose:
1) Telomerase: allows cells to continue to live and divide indefinitely
2) p16: an anti-cancer protein

The genes acted differently in healthy cells and precancerous cells:
Healthy cells: Rise in telomerase and decrease in p16 --> cells live longer.
Precancerous cells: Decrease in telomerase and increase in p16 --> cells die off.

Conclusion: A glucose-restricted diet may help human cells live longer and free of cancer.

Tollefsbol, one of the authors of the study, said:
"These results further verify the potential health benefits of controlling calorie intake… Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body's natural ability to kill off cancer-forming cells… Human longevity can be achieved at the cellular level through caloric restriction.”
They talk about caloric restriction but the study looked at glucose levels. I’m wondering if this has more implications for sugar consumption and the resulting spikes and troughs of blood glucose. Diabetics, for example, who have high levels of blood glucose, suffer from end-organ damage, coronary artery disease, and atherosclerosis, all of which have been associated with telomere shortening.

So… as I’m working on my 2010 resolutions this week, cutting out sugar is definitely on there!

Saturday, December 26, 2009

Meditative medicine: a new distinction

This article in the Hastings Center Report, “Toward a Meaningful Alternative Medicine” by Vinay Prasad, has shifted the way I think about “alternative medicine” and health care in general. He starts by sharing this quote by Phil Fontanarosa and George Lundberg which I instinctively agree with: “There is no alternative medicine… there is only scientifically proven, evidence-based medicine supported by solid data or unproven medicine, for which data is lacking.” Alternative medicine is often considered unscientific and faddish. But then why are so many people drawn to it? Is there more besides “evidence-based medicine” that we are missing? Is health care more than “an unrelenting devotion to outcomes”?

Prasad suggests we think about meditative medicine in parallel with our evidence-based framework. He refers to German philosopher Heidegger’s work contrasting poetry and technology as differing ways of making sense of the world. Technology represents “calculative thinking,” using objects to achieve a purpose. Poetry and art represents “meditative thinking,” reflecting on the beauty inherent in how things are. Both ways of thinking are important. Heidegger was concerned that “the approaching tide of technological revolution in the atomic age could so captivate, bewitch, dazzle, and beguile man that calculative thinking may someday come to be accepted and practiced as the only way of thinking.”

Prasad then applies this to medicine: 
“The worry, if one takes Heidegger’s perspective, is not that health is an outcome to be optimized by cost-effective, evidence-based medicine, but that this might be the only way of thinking about health – that no alternative exists. Unfortunately, practitioners do little to provide a true alternative when they use complementary medicine in purely calculative terms: sometimes but not always relying on randomized controlled trial data, and sometimes but not always trusting anecdotal evidence. Heidegger teaches us that ‘Western’ and ‘alternative’ are not meaningful categories. A better distinction is ‘calculative’ and ‘meditative.’ And what we need is meditative medicine.”
 The point is: we can’t think of all alternative medicine in terms of the evidence-based model, just like we can’t think about art and poetry like we do technology. So, the distinction is as follows:

Calculative medicine: A medical intervention (can be ‘Eastern’ or ‘Western,’ unconventional or mainstream) that is aimed at producing an outcome (such as reduced cancer recurrence, longevity, reduced menopausal symptoms, etc.) that can be studied with evidence-based methodology. Examples of calculative medicine include giving a statin to lower cholesterol, yoga for blood pressure control, or acupuncture for pain control.

Meditative medicine: Meditative medicine includes practices (exercise, eating healthy, meditation, etc) which “are done not with a particular outcome in mind, but as part of living a healthy life… they provide a way of making sense of health, illness, and the good life. Becoming vegetarian because you wish to lower your LDL is calculative. Does it work? A well-designed trial could tell us, but it would miss the point.” Meditative medicine also applies to the patient-doctor relationship: “Allowing doctors to develop relationships with patients beyond what is necessary for good primary care is meditative.”


As Prasad explains:
“Some people exercise because studies have shown a correlation between twenty minutes of aerobic activity and longevity (a calculative view), while others do so because an active life is healthy (a meditative view). Some drink a glass of wine each night because it has been shown to decrease cardiovascular risk (calculative), while others never needed that study to know that drinking wine in moderation, as part of a broader set of practices, is healthy (meditative).”
Meditative medicine is why I’m a vegetarian, why I exercise, why I do yoga... not for a specific outcome that can be studied with randomized controlled trials, but because it feels right and is part of a healthy, balanced lifestyle. It is also why I want to do family medicine and provide both calculative and meditative health care. So much of healing and health is in the patient-doctor relationship, and that is not something that can be measured with RCTs. 

Wednesday, December 23, 2009

An amazing animal

Isn’t man an amazing animal? He kills wildlife by the millions in order to protect his domestic animals and their feed. Then he kills domestic animals by the billions and eats them. This in turn kills man by the millions, because eating all those animals leads to degenerative – and fatal – health conditions like heart disease, kidney disease, and cancer. So then man tortures and kills millions more animals to look for cures for these diseases. Elsewhere, millions of other human beings are being killed by hunger and malnutrition because food they could eat is being used to fatten domestic animals. Meanwhile, some people are dying of sad laughter at the absurdity of man, who kills so easily and so violently, and once a year sends out cards praying for “Peace on Earth.”
~C. David Coates

Saturday, December 19, 2009

Research update: Month 2

A quick update:
  • My telomere study is evolving to be much than I ever initially envisioned. Writing a grant to do real-time PCR analysis on DNA from peripheral blood mononuclear cells? I honestly never thought I would say that. I love thinking about these questions and realizing that I can actually do it. We have two grant proposals due Jan/Feb. 
  • I feel distracted from my initial goal of running a yoga clinical trial. The plan is to submit the yoga study protocol for IRB approval at the end of January. My priority right now is this telomere grant but once I finish that I’ll focus my energies on the protocol. 
  • Instead of recruiting on Fridays (meaning I “cold call” patients in the waiting room trying to persuade them to enroll in a research study – an inefficient and poor use of time), I will now be spending my Fridays seeing patients with an oncologist (and enrolling patients within the trust of the patient-doctor relationship – much more effective). I can now build a relationship with this oncologist and learn about breast cancer management, while also talking with patients about the yoga study and finding future participants. I couldn’t be happier about this. I *almost* liked wearing my short white coat again. 
  • I’ve been neglecting my interest in HIV and infectious disease and I miss it. I’ve been in touch with some HIV physicians I admire and hope to work with them on some small projects.

Thursday, December 17, 2009

Healing process and practice

I’ve been observing myself going through this healing process. At first I felt frustrated, irritable, unmotivated, etc. It’s been over a week and my rib is still hurting, stopping me from practicing normally. But over the past few days I’ve been feeling more content... and actually, I’m kind of starting to enjoy my time off.

Or maybe this new perspective is from “juicing.” I’m on my third day of JUST JUICE (pomegranate, blueberry, carrot, greens & spirulina... anything I can find that’s colorful and antioxidant-filled). I’m getting plenty of calories, but giving my GI tract a much needed rest. And I’m feeling great - energized, steady, attentive. I’d keep it up for longer if it weren’t for all the holiday food to munch on. But maybe I’ll start doing this more regularly, maybe on moon days?

Practice today was slow and tentative, I’m afraid to do anything that might hurt my body (although I did backbends for the first time in a week - they felt good). David said to be “narrow” in what I eat over the holidays, and to make sure to give my body some time without food so it can direct energy towards healing.